The information published on this WEBsite one have only a informative character, 

and they cannot replace the medical visit.

 

 

 

H. P. V. - Human Papilloma Virus

Google

web

gyneconline

 

   

 

  Definition of HPV

The HPV (Human Papilloma Virus) is in charge of several lesions, commonly notes under the name of condylomas, than they (perineo, vulva, vagina and uterine cervix) feminine can themselves be found to level of the genital apparatus inferior, nonthat to genital level male them.                 

 

 

  As the HPV is transmitted   

The HPV is transmitted mostly with the sexual activity. Today one thinks that the infection from HPV is one of the most common  sexually transmitted diseases. Its maximum incidence is had in the persons of age between the 20 and 40 years. It's also  possible the transmission of HPV by means of objects (as an example linen) that they have come to contact with infected persons.               

 

 

  HPV's effects   

The manifestations of the HPV can be variable to second of the interested anatomical districts. The lesions that are developed to perineal and perianal level of the skin, and those that they are developed on the vulva and vagina are visible by rough estimate knot (come therefore defined clinical condylomatose lesions) and are named condylomas. These have the aspect of found lesions, verrucose, of variable dimensions, single or plurime.   To level of the uterine cervix usually the lesions of condilomatos type are not visible to eye knot, but for being recognized by the colposcopic examination (you see the page on the Colposcopy). Often to level of theuterine cervix the lesions from HPV are associated to lesions of displasic type (CIN or Cervical Intraepitelial Neoplasia , or SIL or Squamous Intraepitelial Lesion). Condilomato to cervical level for the fact to be visible by rough estimate the knot does not come defined subclinical.               

 

 

  HPV's diagnosis   

The diagnosis of infection from HPV it can be reached through various methodical.      

  Clinical diagnosis

The lesions that develop to perineal and perianal skin,  named  condylomas, are recognizable by rough estimate knot in occasion of the gynecological visit.  For one they more taken care of appraisal is than aid the vulvoscopy (examinations of the vulva with the aid of the Colposcopy).     

  Pap-test and Colposcopy

The lesions from HPV localized on the uterine cervix are not visible by rough estimate knot, but they can be identified with other means: PAP-test (cytology), Colposcopy, biopsy, immunohistochemistry.    T

The Pap-test allows to identify the koilocytes. The cervical cells called koilocytes manifest to the microscopical examination  alteration due to the action of virus the HPV. Moreover the Pap-test marks it if beyond to the koilocytes one Dysplasias are present cells of displasic type (, or CIN, or SIL).     

The Colposcopy allows to estimate on the uterine cervix the existence and localization of the marked lesions from the Pap-test, and therefore it concurs to characterize with precision the center on which carrying out a aimed biopsy that it will carry, with the histologic examination, to the definitive diagnosis.     

  HPV Test 

Draft of a test that allows to before find the presence of virus the HPV still that the cells of the uterine cervix introduce some visible change. This test concurs therefore to identify with great advance the risk of cervical cancer.   A positive test HPV does not want to say that a woman will develop to a cancer of the cervix, but supplies ulterior information on upgrades them risks and recommends therefore to carry out controls more takes care of to you. And' therefore possible to recognize whichever sign of development of the disease with consequent possibility to make a treatment effective.     In order to carry out test HPV, a champion of cells captures itself in the same way from the cervix that for the Pap test. The champion comes then therefore dipped in a liquid for being transported to the laboratory where he will come analyzed.  The searches evidence that the more effective method in order to find to a stage begin them the signs of a cervical cancer consist in executing a Pap-test with to a test HPV. It has been demonstrated that this arranged approach concurs to find approximately 97% of the diseases of the cervical cancer of high degree.  A Pap-test negative (that is normal) with to a test HPV negative guarantees to 99% to run the truly minimal risk of having or developing a cancer and concurs to return to repeat screening (the Pap-test) to the ruotine intervals.          

 

From the practical point of view test HPV can particularly be useful in the following conditions:    

1 - like integration in the screening of women with more than 35 years. In fact beyond this age he is much probable one that the presence of virus HPV to the high risk is indicative of persistent infection to high risk of degeneration towards serious lesions of the cervix.    

2 - when answers of the Pap-test are had light altered dubbie or whose causes, sometimes, they are not clear not even with the colposcopy, and whose possible evolution is not expectable.    

3 - for  control in the time (the so-called one follow up) of women who have received medical or surgical treatments for lesions of the cervix. In this case test HPV is indispensable in order to estimate the possible persistence of the infection turns them with possibility of recidive of the disease.              



  Therapy

The therapy of the lesions from HPV will be variable according to the type and the center of the lesions to deal.    The present condylomas to level of perineo, vulva and vagina go destroyed by means of electrocoagulation or vaporization with laser. In occasion of the treatment it is opportune to capture some condyloma to subject to histologycal examination to confirm the diagnosis.    As far as the lesions to level of the uterine cervix the eventual association of one Dysplasia and the last degree of this (light, moderated or serious one are determining). In the treatment of these lesions the removed lesion is always recommendable to be able to carry out the histologycal examination of all. Therefore they are advices against those methods to you of treatment that aim at the destruction of the lesion (diatermocoagulazione or vaporization laser) without possibility of histologycal examination. They are instead preferring those treatments that diatermica handle, cervical conisation or laser-conisation ) and possibilities therefore of a its histologycal examination consist in the excision of all the lesion .          

 

 

  Prevention

Being the HPV transmitted most times through the sexual activity, the prevention is based on a careful sexual behavior in preventing every kind of infections. In particular the use of the condom in occasional sexual relationships with infected people and in occasional sexual ntercourse is recommended.    Moreover, for the premature acknowledgment of the infections from HPV and the prevention of the lesions to it associated (dysplasias) he is fundamental to regular control with the Pap-test and, when necessary, with the Colposcopy.

 

 

 

 

 

 

 

 

top